Pregnatol Active Folate + Vit B12 contains folate and vitamin B12 in natural forms, which are active and safely fully exploited in the body. It is intended for women who are preparing and want to become pregnant, as well as pregnant women. The use is recommended in the period before the planned pregnancy and during the entire pregnancy.
Vitamins B9 (folate) and B12 play a role in cell division and contribute to normal psychological function, normal homocysteine metabolism, reduction of fatigue and exhaustion, and normal immune system function. In cooperation with vitamin B12, the folate coenzyme enables the conversion of the aforementioned amino acid homocysteine into methionine.
Low folate levels are a risk factor for neural tube damage in the fetus
Folates contribute to normal amino acid synthesis, maternal tissue growth during pregnancy, and normal blood formation. Low folate levels are a risk factor for neural tube damage in the fetus. The beneficial effect is achieved by an intake of at least 400 µg for at least one month before and three months after conception.
Pregnatol Active Folate + Vit B12 contains folate in active form under the trademark QUATREFOLIC®. Quatrefolic® is folate – glucosamine salt of folic acid, in its natural form. By structure, it is an active form of folic acid – enzymes in the body are not necessary for its activation and exploitation. It is in the form of salt that folates are naturally found in foods (green vegetables). In addition, glucosamine salts are naturally found in our body.
The terms folic acid and folate are often used interchangeably for vitamin B9. It belongs to the vitamins of the B complex, it is soluble in water and necessary for maintaining cellular functions and health, and is especially important in preparation for pregnancy and during pregnancy.
The essential difference between folate and folic acid is that folate is in its natural form, and folic acid is chemically synthesized. The chemically synthesized form – folic acid - cannot be used by our body in this form. It must be activated by an enzyme in the body through four steps. Studies have shown and confirmed that 30 to 50% of women (depending on the country) cannot activate and use the ingested folic acid at all, because genetically they do not have the enzyme that should activate it. In these women, all ingested folic acid remains circulating freely in the blood, potentially causing side effects for both mom and baby. Folate, in its natural, active form, is completely absorbed and utilized with certainty!
Pregnatol Active Folate + Vit B12 contains two natural, active forms of vitamin B12 – methylcobalamin and adenosylcobalamin. They are naturally found in the body. Methylcobalamin – acts in the cell and adenosylcobalamin is found in all tissues and 20% in the blood. It plays an important role in energy production, contributes to the normal function of the nervous system and the normal metabolism of the amino acid homocysteine. These are active forms and that is why the body uses them immediately and completely without any harmful release of molecules.
Furthermore, the most common form of vitamin B12 in vitamin products is cyanocobalamin. It is a chemically synthesized form of vitamin B12, while the other three forms are natural and are found in food and in the body. Chemically synthesized cyanocobalamin in the body cannot be used in this form, but must be activated through enzymes. During its activation, the cyanide molecule is released, which is harmful.
The period of preparation for pregnancy, as well as the pregnancy itself, is a significant time for a woman as a future mother. It is a time when a woman should get and embrace everything that is best for her. A time of care, health and relaxation. It's your time!
Quatrefolic
Quatrefolic is a salt of folic acid, and it is the form in which it naturally occurs in food. It plays an exceptional role in the body during pregnancy.
Vitamin B12
Two forms of vitamin B12 – methylcobalamin and adenosylcobalamin. The body immediately utilizes them without any harmful release in the body.
I want to get pregnant
1 capsule daily, 12 weeks before the planned pregnancy.
I'm pregnant
1 capsule daily, throughout the entire pregnancy.
Folate intake during pregnancy is necessary for adequate development of the fetus and placenta and for the long-term health of the individual. Its deficiency can cause fetal pathologies, including neural tube disease.
The actual strategy adopted by European countries (including Italy) suggests that women take 0.4 mg of folic acid before conception.
Lack of vitamin B12 in pregnancy is prevalent and is associated with lower birth weight (birth weight <2500 g) and premature birth (gestation length <37 weeks).
Low maternal folate status during pregnancy and lactation remains a significant cause of maternal morbidity in some communities. Folic acid status of the neonate tends to be protected at the expense of maternal stores; However, there is increasing evidence that inadequate maternal folate status during pregnancy can lead to low birth weight in the newborn, thereby creating a risk of developmental and long-term negative health outcomes.
Use is recommended 12 weeks prior to planned pregnancy and throughout pregnancy. It is intended for women who are preparing and want to become pregnant, as well as pregnant women during pregnancy.
Folate and folic acid are essentially the same. The difference is in the shape. Folate is a form of salt, in which it is naturally found in food, and folic acid is a chemical, synthetic form.
Folic acid, as a synthetic form, is less absorbed and used in the body, and as it has been proven, some women cannot use it at all. This is because they do not have an enzyme to activate it. Therefore, 30-50% of women do not even activate and use folic acid in the body. Folic acid that is introduced into the body remains to circulate freely in the blood, potentially causing side effects for both mom and baby.
Therefore, it is best to apply it in the form in which it is naturally found in foods, i.e. as an active folate.
Vitamin B12 plays an extremely important role for the normal function of the nervous system. It is involved in the formation of red blood cells – they cannot be properly created and multiplied without vitamin B12. Vitamin B12 contributes to the maintenance of normal energy metabolism as well as normal homocysteine metabolism.
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