Peanut allergy is one of the most common and potentially severe food allergies in children. It represents an immune-mediated reaction to peanut proteins and may manifest with mild skin symptoms or severe systemic reactions. A modern approach to pediatric allergies includes early diagnosis, strict allergen avoidance, preparedness for emergency situations, and long-term support of immune balance, including nutritional factors involved in inflammation regulation.

TL;DR – Quick Answer
- Peanut allergy is an immune reaction to peanut proteins
- It can develop early in childhood and often persists into adulthood
- Symptoms range from mild skin reactions to anaphylaxis
- In addition to allergen avoidance, long-term immune support is important
What Is Peanut Allergy?
Peanut allergy is an IgE-mediated allergic reaction that occurs when the immune system mistakenly identifies peanut proteins as harmful. In response, the body releases mediators such as histamine, leading to the development of allergic symptoms.
Peanuts are among the most common food allergens in children, and peanut allergy is often persistent. Unlike some other childhood food allergies (such as milk or egg allergy), it frequently continues into adulthood.
(Source: https://pubmed.ncbi.nlm.nih.gov/29431373/)
How Common Is Peanut Allergy in Children?
Epidemiological data show that the prevalence of peanut allergy has increased significantly over recent decades, particularly in developed countries. Current estimates indicate that peanut allergy affects approximately 1–2% of children in Europe and North America.
Studies demonstrate that the prevalence of peanut allergy has more than doubled over the past 20–30 years, making it a major public health concern in pediatric allergy.
(Source: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6679030/)
Symptoms of Peanut Allergy
Symptoms typically occur shortly after exposure to peanuts and may include:
- Skin reactions (urticaria, redness, itching)
- Swelling of the lips, tongue, or face
- Gastrointestinal symptoms (nausea, vomiting, abdominal pain)
- Respiratory symptoms (wheezing, difficulty breathing)
In severe cases, peanut allergy can lead to anaphylaxis, a life-threatening systemic reaction that requires immediate medical attention.
Estimates suggest that peanut allergy is responsible for approximately 20–30% of food-induced anaphylaxis cases in children, highlighting the importance of early diagnosis and strict allergen avoidance.
(Source: https://pubmed.ncbi.nlm.nih.gov/30878330/)
Why Is Peanut Allergy Often Associated with Atopic Dermatitis?
Children with atopic dermatitis have an impaired skin barrier, which may allow easier penetration of environmental allergens. Scientific evidence indicates that allergen exposure through damaged skin can contribute to the development of food allergies, including peanut allergy.
This association explains why peanut allergy is more frequently observed in children with:
- Atopic dermatitis
- A family history of allergic diseases
Research shows that children with moderate to severe atopic dermatitis have a 2–6 times higher risk of developing food allergies, including peanut allergy, compared with children without skin barrier dysfunction.
It is important to emphasize that atopic dermatitis does not directly cause peanut allergy, but it represents a risk factor for sensitization, with the risk being higher in children with more severe forms of the disease.
(Source: https://pubmed.ncbi.nlm.nih.gov/30388433/)
Immune System, Inflammation, and Allergic Response
Allergic diseases result from dysregulation of the immune response, characterized by excessive activation of inflammatory pathways. Chronic inflammation represents a shared mechanism underlying allergic and atopic conditions.
Nutritional factors such as:
- Omega-3 fatty acids
- Vitamin D
play a role in modulating immune responses and maintaining immune balance. Meta-analyses of clinical studies suggest that omega-3 fatty acids may help reduce levels of certain inflammatory markers, including cytokines involved in allergic reactions.
Studies also indicate that children with lower omega-3 intake may exhibit a more pronounced inflammatory response, which may be relevant in allergic and atopic conditions.
(Sources: https://pubmed.ncbi.nlm.nih.gov/32948857/, https://pubmed.ncbi.nlm.nih.gov/30611908/)
Nutritional Support as Part of a Long-Term Approach
The modern approach to allergies in children is primarily based on avoidance of the confirmed allergen, family education, and having an emergency action plan in place. In addition, the role of nutritional factors in supporting normal immune system function is being investigated. In this context, formulations combining omega-3 fatty acids, gamma-linolenic acid (GLA), and vitamin D are used to support normal immune function and help regulate inflammatory processes.
As part of such an approach, MegoKid Allergy & Atopic is used as a daily nutritional support for children with allergies and atopic conditions, in accordance with age-specific recommendations and pediatric guidance.
Key Numbers at a Glance
- 1–2% of children have peanut allergy
- 2–6x higher risk in children with atopic dermatitis
- 20–30% of food-induced anaphylaxis cases are related to peanuts
- Omega-3 fatty acids are associated with lower inflammatory markers
Clinical Conclusions
- Peanut allergy is a common and potentially severe food allergy
- It is frequently associated with atopic dermatitis and impaired skin barrier function
- Immune dysregulation and inflammation are central mechanisms
- Nutritional support may be considered part of a comprehensive, long-term management strategy
Frequently Asked Questions (FAQ)
Does peanut allergy resolve on its own?
In most children, peanut allergy persists into later childhood or adulthood.
Can small amounts of peanuts be dangerous?
Yes. Even minimal exposure can trigger a reaction in sensitized children.
Can peanut allergy be prevented?
There is no guaranteed prevention, but early diagnosis and appropriate management are essential.
Do supplements cure peanut allergy?
No. Supplements are not a treatment for allergy but may be part of a broader approach to immune support.
References